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Monoglycerides - fatty acids with special effects

Medium chained fatty acids (MCFA) are well proven in animal feeds in order to stabilize health- and performance-parameters during challenging phases of animal production. Medium chained monoglycerides of fatty acids (MCM) are the advancement of MCFA and show an even better effect on inhibition of bacteria growth in intestine. SCHAUMANN leverages this new knowledge in it's production.



Monoglycerides (MCM) inhibit undesirable microorganism


Monoglycerides (MCM) show a broad spectrum of efficacy. In intestinal tract they verifiably inhibit growth of gram positive as well as gram negative bacteria. They damage the protective cover (cell membrane) of bacteria and simultaneously disturb metabolic processes aas well as the intracell immune system.


Due to suppression of undesirable bacteria, development of desired intestinal flora is stimulated. Even gram-positive bacteria like clostridia, streptococci and staphylococci (that are very tough and resistant becauses of their thick murein layer) are suppressed effectively.



Monoglycerides - special form of medium-chained fatty acids


Monoglycerides (MCM) are formed, by bounding a MCFA to glycerol via an esterification process (see Fig. 1) The effects of individual MCM are even strengthened by clever combinations of different MCMs.




Figure 1: schematic representation - molecules of medium chained fatty acids and their monoglycerides (MCM)


Mechanism of penetration into the cell and disturbance of metabolic processes


Figure 2 shows the mechanism schematically. Because of its chemical and physical characteristics, the MCM-molecule is easily absorbed into the cell. Simultaneously, permeability of the cell wall gets increased and structure is modified. Inside the cell, enzymes break down the bonding of glycerol and fatty acids. Subsequently pH-value drops and the germ inhibiting mode of action sets in.

The now free fatty acids destroy metabolic balance as well as DNA of cell. Pathogenic bacteria are not able to maintain their viability anymore, since MCMs have inhibited relevant mechanism in multiple modes of action.



Figure 2: schematic mechanism of Monogylcerides (MCM)


 Advantages of MCMs are there efficiency and positive fodder properties


MCM are taste- and odourless, because of their polarity they are emulisifiable and show great effects even at high pH levels and low dosage rates. To inhibit growth of gram positive bacteria, considerably lower inclusion rates are necessary. The neutral odour lead to an excellent acceptance, without any negative effect on feed intake, allowing high flexibility in application and used quantity.


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